Title : Purification and characterization of hamster liver microsomal 7alpha-hydroxycholesterol dehydrogenase. Similarity to type I 11beta-hydroxysteroid dehydrogenase.

Pub. Date : 1998 Jun 26

PMID : 9632680






1 Functional Relationships(s)
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1 Since 7-oxocholesterol is a potent inhibitor of cholesterol 7alpha-hydroxylase, alternative mechanisms for regulation of bile acid synthesis may exist in human and hamster liver due to production of this metabolite and its potential as an oxysterol. 7-ketocholesterol cytochrome P450 family 7 subfamily A member 1 Homo sapiens