Pub. Date : 1998 Apr 28
PMID : 9630707
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Niemann-Pick disease type C (NP-C) is an autosomal recessive disorder characterized by the sequestration and trapping of endocytosed cholesterol in lysosomes. | Cholesterol | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 2 | Niemann-Pick disease type C (NP-C) is an autosomal recessive disorder characterized by the sequestration and trapping of endocytosed cholesterol in lysosomes. | Cholesterol | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 3 | Levels of free cholesterol in whole cell homogenates increased about 1.5-fold in human NP-C fibroblasts and mouse SPM-3T3 cells, while in the plasma membrane, cholesterol content did not significantly change in NP-C fibroblasts but rather decreased in SPM-3T3 cells. | Cholesterol | NPC intracellular cholesterol transporter 1 | Homo sapiens |