Pub. Date : 1998 Jun
PMID : 9584169
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10. | Glycogen | cyclin-dependent serine/threonine-protein kinase PHO85 | Saccharomyces cerevisiae S288C |
| 2 | Pho85 has also been implicated as a kinase that phosphorylates and negatively regulates glycogen synthase (Gsy2), and deletion of PHO85 causes glycogen overaccumulation. | Glycogen | cyclin-dependent serine/threonine-protein kinase PHO85 | Saccharomyces cerevisiae S288C |
| 3 | Mutation of PHO85 suppressed the glycogen storage deficiency of snf1 or glc7-1 mutants in which glycogen synthase is locked in an inactive state. | Glycogen | cyclin-dependent serine/threonine-protein kinase PHO85 | Saccharomyces cerevisiae S288C |
| 4 | This genetic result suggests an additional role for Pho85 in the negative regulation of glycogen accumulation that is independent of Pcl8 and Pcl10. | Glycogen | cyclin-dependent serine/threonine-protein kinase PHO85 | Saccharomyces cerevisiae S288C |