Title : Arginine vasopressin stimulates phospholipid methylation in cultured rat mesangial cells: possible role for PGE2 production.

Pub. Date : 1998 Feb

PMID : 9578155






4 Functional Relationships(s)
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1 The production of PGE2 increased with AVP treatment, and the decline in methylated phospholipids paralleled the release of PGE2 in AVP-stimulated cells. Dinoprostone arginine vasopressin Rattus norvegicus
2 The production of PGE2 increased with AVP treatment, and the decline in methylated phospholipids paralleled the release of PGE2 in AVP-stimulated cells. Dinoprostone arginine vasopressin Rattus norvegicus
3 The inhibition of phospholipid methylation by treatment with adenosyl-S-isobutyl mercaptan (SIBA) resulted in a marked decrease in AVP-stimulated PGE2 production. Dinoprostone arginine vasopressin Rattus norvegicus
4 These findings indicate that AVP stimulates phospholipid methylation in cultured rat mesangial cells and phosphatidylcholine, synthesized by a transmethylation pathway, may be a source for PGE2 production. Dinoprostone arginine vasopressin Rattus norvegicus