Title : Deletion of a highly motional residue affects formation of the Michaelis complex for Escherichia coli dihydrofolate reductase.

Pub. Date : 1998 May 5

PMID : 9572847






1 Functional Relationships(s)
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1 The introduction of glycine into the modified betaF-betaG loop, however, generally eliminated conformational changes required by DeltaG121 DHFR to attain the Michaelis complex. Glycine Dihydrofolate reductase Escherichia coli