Title : Paracetamol hepatotoxicity in metallothionein-null mice.

Pub. Date : 1998 Feb 6

PMID : 9570328






1 Functional Relationships(s)
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1 Investigation of lower PCT doses (< or = 120 mg/kg) in fasted mice over 24 h demonstrated a greater susceptibility in female MT -/- mice with plasma LD, 2.4-fold and ALT, 7.5-fold greater than in MT +/+ mice at 120 mg/kg PCT. Acetaminophen glutamic pyruvic transaminase, soluble Mus musculus