Title : Effect of hyperglycemia on pyruvate dehydrogenase activity and energy metabolites during ischemia and reperfusion in gerbil brain.

Pub. Date : 1998 Mar 30

PMID : 9555066






1 Functional Relationships(s)
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1 During reperfusion, PDH activities were suppressed corresponding to the poor recovery of ATP and PCr concentrations and the increase in lactate concentration in the hyperglycemic group, suggesting that preischemic hyperglycemia may impair metabolism by suppressing PDH activity. Lactic Acid pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens