Title : Preventive effects of the deleted form of hepatocyte growth factor against various liver injuries.

Pub. Date : 1998 Jan 26

PMID : 9548396






2 Functional Relationships(s)
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1 The pretreatment of rats and mice with the deleted form of HGF prevented the liver injuries and coagulopathy induced by endotoxin, dimethylnitrosamine and acetaminophen and reduced the mortality due to hepatic dysfunction induced by these hepatotoxins. Dimethylnitrosamine hepatocyte growth factor Mus musculus
2 The concurrent administration of the deleted form of HGF also prevented the liver injury and hepatic fibrosis in mice treated with alpha-naphthylisothiocyanate and in rats treated with dimethylnitrosamine. Dimethylnitrosamine hepatocyte growth factor Mus musculus