Title : Stimulation of renin secretion by nitric oxide is mediated by phosphodiesterase 3.

Pub. Date : 1998 Apr 14

PMID : 9539809






1 Functional Relationships(s)
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1 Inhibition of PDE-3 by 20 micromol/liter of milrinone or by 200 nmol/liter of trequinsin caused a 5- to 6-fold stimulation of renin secretion that was slightly enhanced by NO synthase inhibition and moderately attenuated by NO donation. Milrinone renin Homo sapiens