Title : Accumulation of cholesterol and GM2 ganglioside in cells cultured in the presence of progesterone: an implication for the basic defect in Niemann-Pick disease type C.

Pub. Date : 1998 Jan

PMID : 9533562






6 Functional Relationships(s)
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1 Accumulation of cholesterol and GM2 ganglioside in cells cultured in the presence of progesterone: an implication for the basic defect in Niemann-Pick disease type C. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
2 Cultured fibroblasts from patients with Niemann-Pick disease type C (NP-C) are characterized by lysosomal accumulation of unesterified cholesterol and a defect in intracellular trafficking of cholesterol. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
3 Cultured fibroblasts from patients with Niemann-Pick disease type C (NP-C) are characterized by lysosomal accumulation of unesterified cholesterol and a defect in intracellular trafficking of cholesterol. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
4 Cultured fibroblasts from patients with Niemann-Pick disease type C (NP-C) are characterized by lysosomal accumulation of unesterified cholesterol and a defect in intracellular trafficking of cholesterol. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
5 Cultured fibroblasts from patients with Niemann-Pick disease type C (NP-C) are characterized by lysosomal accumulation of unesterified cholesterol and a defect in intracellular trafficking of cholesterol. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
6 The accumulation of free cholesterol and GM2 ganglioside may be a clue for understanding the basic defect of NP-C. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens