Pub. Date : 1998 Mar
PMID : 9519755
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Diabetes or experimental galactosemia of 2 months" duration resulted in > 50% elevation of PKC activity in the retina, and administration of LY333531 prevented the elevation. | ruboxistaurin | protein kinase C, gamma | Rattus norvegicus |
2 | Retinal microvessels, the main site of lesions in diabetic retinopathy, likewise showed elevated activity of PKC and inhibition of ATPases in diabetes and in experimental galactosemia, and administration of LY333531 to diabetic animals prevented these abnormalities. | ruboxistaurin | protein kinase C, gamma | Rattus norvegicus |