Title : Effects of pentylenetetrazol kindling on glutamate receptor genes expression in the rat hippocampus.

Pub. Date : 1998 Mar 2

PMID : 9518693






2 Functional Relationships(s)
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1 In order to test this hypothesis, we investigated the effects of pentylenetetrazol kindling on the expression of genes coding for NMDAR1 and GluR2 in the rat hippocampal formation. Pentylenetetrazole glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus
2 Pentylenetetrazol kindling decreased the hippocampal NMDAR1 mRNA level after 3 and 24 h; lowered the GluR2 flip level and elevated the flop mRNA one in the CA1 field and dentate gyrus after 3 and 24 h, respectively. Pentylenetetrazole glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus