Pub. Date : 1998 Mar 27
PMID : 9516417
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Functional analysis of disulfide linkages clustered within the amino terminus of human apolipoprotein B. | Disulfides | apolipoprotein B | Homo sapiens |
| 2 | We tested the involvement of N-terminal six disulfide bonds (Cys-1 through Cys-12) of human apolipoprotein (apo) B in the assembly and secretion of lipoproteins using two C-terminal-truncated apoB variants, namely B50 and B18. | Disulfides | apolipoprotein B | Homo sapiens |
| 3 | Expression of these mutants showed that disruption of disulfide bond formation within Cys-5 to Cys-8 diminished apoB secretion, whereas within Cys-1 to Cys-4 or Cys-9 to Cys-12 had lesser or no effect. | Disulfides | apolipoprotein B | Homo sapiens |