Title : Inhibition of T cell activation by pharmacologic disruption of the MEK1/ERK MAP kinase or calcineurin signaling pathways results in differential modulation of cytokine production.

Pub. Date : 1998 Mar 15

PMID : 9510155






1 Functional Relationships(s)
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1 FK506 also reduced CD3/CD28-induced production of IL-3, IL-4, IL-10, TNF-alpha, and IL-6 but augmented that of GM-CSF, IL-5, IFN-gamma, and IL-13. Tacrolimus CD28 molecule Homo sapiens