Title : Regulation of the human interleukin-2 gene by the alpha and beta isoforms of the glucocorticoid receptor.

Pub. Date : 1997 Dec 31

PMID : 9510064






1 Functional Relationships(s)
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1 Using a recently developed transfection technique, we demonstrate that in primary human lymphocytes, stimulation of a 548 bp IL-2 promoter-luciferase reporter construct by phorbol ester and calcium ionophore is reversed by dexamethasone to a similar extent as in Jurkat T lymphoma cells transfected with a GRalpha expression vector. Calcium interleukin 2 Homo sapiens