Pub. Date : 1998 Mar
PMID : 9488468
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent. | geldanamycin | tumor protein p53 | Homo sapiens |
2 | To examine the effect of directly disrupting chaperone interactions with mutant p53, we made use of geldanamycin (GA), a selective hsp90-binding agent which has been shown to alter the chaperone associations regulating the function of unliganded steroid receptors. | geldanamycin | tumor protein p53 | Homo sapiens |
3 | To examine the effect of directly disrupting chaperone interactions with mutant p53, we made use of geldanamycin (GA), a selective hsp90-binding agent which has been shown to alter the chaperone associations regulating the function of unliganded steroid receptors. | geldanamycin | tumor protein p53 | Homo sapiens |
4 | GA treatment of cells altered heteroprotein complex formation with several different mutant p53 species. | geldanamycin | tumor protein p53 | Homo sapiens |