Pub. Date : 1998 Feb
PMID : 9486255
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Time- and dose-dependent TNF-alpha-stimulated ICAM-1 and E-selectin upregulation and neutrophil adhesion each were suppressed by tyrosine kinase inhibitors, including genistein (200 microM), but not genistein, its isoflavone analog without tyrosine kinase inhibitory activity. | Genistein | tumor necrosis factor | Homo sapiens |
2 | Tyrosine phosphorylation of two proteins (85 and 145 kDa in the cytoskeleton fraction) found minutes after TNF-alpha-stimulation was also inhibited by genistein. | Genistein | tumor necrosis factor | Homo sapiens |