Title : The Ca(2+)-dependent interaction of S100B(beta beta) with a peptide derived from p53.

Pub. Date : 1998 Feb 17

PMID : 9485322






1 Functional Relationships(s)
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1 In this paper, we report that S100B(beta beta) binds to the p53 peptide (CaK3 < or = 23.5 +/- 6.6 microM) in a Ca(2+)-dependent manner, and that the presence of the p53 peptide was found to increase the binding affinity of Ca2+ to S100B(beta beta) by 3-fold using EPR and PRR methods, whereas the peptide had no effect on Zn2+ binding to S100B(beta beta). Zinc tumor protein p53 Homo sapiens