Title : Polyethylene glycol conjugation of recombinant methioninase for cancer therapy.

Pub. Date : 1998 Feb

PMID : 9473456






2 Functional Relationships(s)
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1 In order to prevent immunological reactions which might be produced by multiple dosing of rMETase and to prolong the serum half-life of rMETase, the N-hydroxysuccinimidyl ester of methoxypolyethylene glycol propionic acid (M-SPA-PEG 5000) has been coupled to rMETase. methoxypolyethylene glycol propionic acid granzyme M Rattus norvegicus
2 In order to prevent immunological reactions which might be produced by multiple dosing of rMETase and to prolong the serum half-life of rMETase, the N-hydroxysuccinimidyl ester of methoxypolyethylene glycol propionic acid (M-SPA-PEG 5000) has been coupled to rMETase. methoxypolyethylene glycol propionic acid granzyme M Rattus norvegicus