Title : Inhibitory effect of adenosine on degranulation of human cultured mast cells upon cross-linking of Fc epsilon RI.

Pub. Date : 1998 Jan 26

PMID : 9464280






3 Functional Relationships(s)
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1 Inhibitory effect of adenosine on degranulation of human cultured mast cells upon cross-linking of Fc epsilon RI. Adenosine Fc epsilon receptor Ia Homo sapiens
2 Adenosine inhibited Fc epsilon RI-mediated tryptase release from HCMC in a dose-dependent manner, and this inhibitory effect was completely blocked by the A2a receptor antagonist ZM241385. Adenosine Fc epsilon receptor Ia Homo sapiens
3 These results suggest that adenosine acts via A2 receptors to inhibit Fc epsilon RI-mediated mediator release from human mast cells. Adenosine Fc epsilon receptor Ia Homo sapiens