Title : CRP interacts with promoter-bound sigma54 RNA polymerase and blocks transcriptional activation of the dctA promoter.

Pub. Date : 1998 Feb 2

PMID : 9451003






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When the CRP-binding sites are deleted, CRP still interacts in a cAMP-dependent manner with the stable Esigma54 closed complex via protein-protein contacts. Cyclic AMP C-reactive protein Homo sapiens
2 When the CRP-binding sites are deleted, CRP still interacts in a cAMP-dependent manner with the stable Esigma54 closed complex via protein-protein contacts. Cyclic AMP C-reactive protein Homo sapiens
3 Thus, Esigma54 promoters are responsive to CRP, a protein unrelated to sigma54 activators, and the repression exerted is the direct result of an interaction between Esigma54 and the CRP-cAMP complex. Cyclic AMP C-reactive protein Homo sapiens
4 Thus, Esigma54 promoters are responsive to CRP, a protein unrelated to sigma54 activators, and the repression exerted is the direct result of an interaction between Esigma54 and the CRP-cAMP complex. Cyclic AMP C-reactive protein Homo sapiens