Title : An active-site histidine of NR1/2C mediates voltage-independent inhibition by zinc.

Pub. Date : 1997 Dec 1

PMID : 9450689






3 Functional Relationships(s)
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Protein Name
Organism
1 An active-site histidine of NR1/2C mediates voltage-independent inhibition by zinc. Histidine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
2 Reduction of zinc inhibition of NR1/2C heteromers was seen after labeling with the histidine-modifying reagent diethylpyrocarbonate. Histidine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
3 This finding suggests that the NR1/2C heteromeric ion channel contains an active-site histidine responsible for zinc inhibition. Histidine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis