Title : A tacrolimus-related immunosuppressant with reduced toxicity.

Pub. Date : 1998 Jan 15

PMID : 9448138






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 BACKGROUND: Tacrolimus (FK506) has potent immunosuppressive properties reflecting its ability to block the transcription of lymphokine genes in activated T cells through formation of a complex with FK506 binding protein-12, which inhibits the phosphatase activity of calcineurin. Tacrolimus FK506 binding protein 1a Mus musculus
2 BACKGROUND: Tacrolimus (FK506) has potent immunosuppressive properties reflecting its ability to block the transcription of lymphokine genes in activated T cells through formation of a complex with FK506 binding protein-12, which inhibits the phosphatase activity of calcineurin. Tacrolimus FK506 binding protein 1a Mus musculus