Title : Developmental regulation of glutamate and GABA(A) receptor gene expression in rat hippocampus following kainate-induced status epilepticus.

Pub. Date : 1997

PMID : 9445090






1 Functional Relationships(s)
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1 In adult rats, kainic acid-induced status epilepticus markedly reduces GluR2 (the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid, AMPA subunit that limits Ca2+ permeability), receptor mRNA in the vulnerable CA3 and may contribute to delayed neurodegeneration. Kainic Acid glutamate ionotropic receptor AMPA type subunit 2 Rattus norvegicus