Pub. Date : 1997 Dec 1
PMID : 9436302
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structure and serotonin 5-HT2C receptor activity of ortho- and meta-substituted phenylpiperazines. | phenylpiperazine | 5-hydroxytryptamine receptor 2C | Homo sapiens |
| 2 | The structural characteristics of ortho- and meta-substituted phenylpiperazines have been investigated in order to understand their actions at the serotonin 5-HT2C receptor. | phenylpiperazine | 5-hydroxytryptamine receptor 2C | Homo sapiens |
| 3 | The activities of several phenylpiperazines, in combination with their crystal structures and conformational characteristics, lead to the hypothesis that the conformation for which the piperazine ring and the phenyl ring are approximately co-planar should be the 5-HT2C receptor "activating" conformation. | phenylpiperazine | 5-hydroxytryptamine receptor 2C | Homo sapiens |