Title : Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L.

Pub. Date : 1998 Jan 12

PMID : 9425165






1 Functional Relationships(s)
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1 However, the protease CPP32, a downstream molecule of the CD95 pathway, was activated in UV-exposed HaCaT cells, and UV-induced apoptosis was blocked by the ICE protease inhibitor zVAD, implying that at least similar downstream events are involved in CD95- and UV-induced apoptosis. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 1 Homo sapiens