Pub. Date : 1998 Jan 6
PMID : 9419378
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These compounds (i) suppress the association rate of guanosine 5"-[gamma-thio]triphosphate ([35S]GTP[gammaS]) binding to Gsalpha-s but not to Gialpha-1, (ii) inhibit stimulation of adenylyl cyclase activity in S49 cyc- membranes (deficient in endogenous Gsalpha) by exogenously added Gsalpha-s, and (iii) block the coupling of beta-adrenergic receptors to Gs with half-maximum effects in the low micromolar range. | Sulfur-35 | GNAS complex locus | Homo sapiens |
| 2 | These compounds (i) suppress the association rate of guanosine 5"-[gamma-thio]triphosphate ([35S]GTP[gammaS]) binding to Gsalpha-s but not to Gialpha-1, (ii) inhibit stimulation of adenylyl cyclase activity in S49 cyc- membranes (deficient in endogenous Gsalpha) by exogenously added Gsalpha-s, and (iii) block the coupling of beta-adrenergic receptors to Gs with half-maximum effects in the low micromolar range. | Sulfur-35 | GNAS complex locus | Homo sapiens |
| 3 | These compounds (i) suppress the association rate of guanosine 5"-[gamma-thio]triphosphate ([35S]GTP[gammaS]) binding to Gsalpha-s but not to Gialpha-1, (ii) inhibit stimulation of adenylyl cyclase activity in S49 cyc- membranes (deficient in endogenous Gsalpha) by exogenously added Gsalpha-s, and (iii) block the coupling of beta-adrenergic receptors to Gs with half-maximum effects in the low micromolar range. | Sulfur-35 | GNAS complex locus | Homo sapiens |