Title : Proteolytic profile of recombinant pro-opiomelanocortin in embryonal carcinoma P19 cells: conversion to beta-lipotropin and secretion are inhibited following incubation with canavanine.

Pub. Date : 1997

PMID : 9404643






1 Functional Relationships(s)
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1 As for other peptide precursors in endocrine cells, the conversion of POMC in P19 cells was inhibited by the biosynthetic replacement of its arginine residues by the analog canavanine. Arginine proopiomelanocortin Homo sapiens