Title : A T42A Ran mutation: differential interactions with effectors and regulators, and defect in nuclear protein import.

Pub. Date : 1997 Dec

PMID : 9398678






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In contrast to wild-type Ran, T42A-Ran.GTP binds very weakly or not detectably to three proposed Ran effectors, Ran-binding protein 1 (RanBP1), Ran-binding protein 2 (RanBP2, a nucleoporin), and karyopherin beta (a component of the nuclear protein import pathway), and is not stimulated to hydrolyze bound GTP by Ran GTPase-activating protein, RanGAP1. Guanosine Triphosphate RAN binding protein 1 Homo sapiens