Title : Re-expression of elafin in 21MT2 breast carcinomas by phorbol 12-myristate 13-acetate is mediated by the Ap1 site in the elafin promoter.

Pub. Date : 1997 Oct 15

PMID : 9377579






3 Functional Relationships(s)
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1 Re-expression of elafin in 21MT2 breast carcinomas by phorbol 12-myristate 13-acetate is mediated by the Ap1 site in the elafin promoter. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 By deletion analysis and mutagenesis, we have identified the Ap1 site in the promoter as the cis element mediating transcriptional activation of elafin in 70N normal breast cells and its induction by phorbol 12-myristate 13-acetate (PMA) in 21MT2 breast tumors. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
3 By deletion analysis and mutagenesis, we have identified the Ap1 site in the promoter as the cis element mediating transcriptional activation of elafin in 70N normal breast cells and its induction by phorbol 12-myristate 13-acetate (PMA) in 21MT2 breast tumors. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens