Title : Short stature and failure of pubertal development in thalassaemia major: evidence for hypothalamic neurosecretory dysfunction of growth hormone secretion and defective pituitary gonadotropin secretion.

Pub. Date : 1997 Oct

PMID : 9365067






1 Functional Relationships(s)
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1 CONCLUSION: Reduced GH secretion and low IGF-I in thalassaemic patients are related to a neurosecretory dysfunction due to iron overload rather than to liver damage. Iron insulin like growth factor 1 Homo sapiens