Pub. Date : 1997 Oct
PMID : 9364925
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme. | Steroids | UDP glucuronosyltransferase family 2 member B17 | Homo sapiens |
| 2 | UGT2B17 is a UDP-glucuronosyltransferase enzyme expressed in several extrahepatic steroid target tissues, including the human prostate, where it glucuronidates C19 steroids such as dihydrotestosterone (DHT), androsterone (ADT), and androstane-3alpha, 17beta-diol (3alpha-diol). | Steroids | UDP glucuronosyltransferase family 2 member B17 | Homo sapiens |
| 3 | This study demonstrates regulation of the UGT2B17 gene by physiological effectors of the human prostate and supports the hypothesis that UGT enzymes are involved in steroid metabolism in extrahepatic tissues. | Steroids | UDP glucuronosyltransferase family 2 member B17 | Homo sapiens |