Title : Metabolism of the antiandrogenic drug (Flutamide) by human CYP1A2.

Pub. Date : 1997 Nov

PMID : 9351907






2 Functional Relationships(s)
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Protein Name
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1 In assays performed using this cell line transfected with the cDNA for the androgen receptor, flutamide is a pure antagonist, and 2-hydroxyflutamide, while a more potent androgen receptor (AR) antagonist, activates the AR at higher concentrations. hydroxyflutamide androgen receptor Homo sapiens
2 In assays performed using this cell line transfected with the cDNA for the androgen receptor, flutamide is a pure antagonist, and 2-hydroxyflutamide, while a more potent androgen receptor (AR) antagonist, activates the AR at higher concentrations. hydroxyflutamide androgen receptor Homo sapiens