Title : Intracellular Ca2+ dependence of nitric oxide mediated enhancement of interleukin-8 secretion in human endothelial cells.

Pub. Date : 1997 Sep 29

PMID : 9350989






2 Functional Relationships(s)
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1 SKF 96365, which has been shown to block receptor mediated Ca2+ entry, and TMB-8, which blocks intracellular Ca2+ release, both inhibited IL-8 secretion, particularly when TNFalpha was used as a costimulator, indicating that [Ca2+]i changes are important components of IL-8 induction by NO.. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate C-X-C motif chemokine ligand 8 Homo sapiens
2 SKF 96365, which has been shown to block receptor mediated Ca2+ entry, and TMB-8, which blocks intracellular Ca2+ release, both inhibited IL-8 secretion, particularly when TNFalpha was used as a costimulator, indicating that [Ca2+]i changes are important components of IL-8 induction by NO.. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate C-X-C motif chemokine ligand 8 Homo sapiens