Title : Dietary fatty acids influence the activity and metabolic control of mitochondrial carnitine palmitoyltransferase I in rat heart and skeletal muscle.

Pub. Date : 1997 Nov

PMID : 9349840






3 Functional Relationships(s)
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1 The fatty acid composition of the diet has been found to influence the activity and sensitivity of mitochondrial carnitine palmitoyltransferase I (CPT I; EC 2.3.1.21) to inhibition by malonyl CoA in rat heart and skeletal muscle. Fatty Acids carnitine palmitoyltransferase 1B Rattus norvegicus
2 However, because manipulation of the nutritional state in these previous studies was restricted mainly to examining the effect of starvation, this study was undertaken to determine whether, as in liver, the fatty acid content and composition of the diet can regulate the activity and metabolic control of CPT I in heart and skeletal muscle. Fatty Acids carnitine palmitoyltransferase 1B Rattus norvegicus
3 These studies indicate that the fatty acid composition of the diet is involved in the regulation of mitochondrial CPT I activity in heart and skeletal muscle. Fatty Acids carnitine palmitoyltransferase 1B Rattus norvegicus