Title : Cellular mechanisms involved during oxytocin-induced prostaglandin F2alpha production in endometrial epithelial cells in vitro: role of cyclooxygenase-2.

Pub. Date : 1997 Nov

PMID : 9348208






2 Functional Relationships(s)
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1 Addition of indomethacin (1 microM) and a specific COX-2 inhibitor (NS-398, 1 microM) blocked the OT-induced PGF2alpha production. Dinoprost cytochrome c oxidase II, mitochondrial Rattus norvegicus
2 Collectively, these results demonstrate, for the first time, that COX-2 is involved in the mechanism by which OT regulates PGF2alpha production in the endometrium. Dinoprost cytochrome c oxidase II, mitochondrial Rattus norvegicus