Pub. Date : 1997 Sep
PMID : 9338146
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The inability of cells to grow in low iron correlates with increasing activity of their iron regulatory protein (IRP). | Iron | Wnt family member 2 | Homo sapiens |
| 2 | We demonstrated that the activity (ratio activated/total) of the iron regulatory protein (IRP) in HID cells Jiyoye and K562 increased more than twofold (from 0.32 to 0.79 and from 0.47 to 1.12, respectively) within 48 h after their transfer into low-iron medium. | Iron | Wnt family member 2 | Homo sapiens |
| 3 | Addition of iron chelator deferoxamine (50 microM, i.e., about half-maximal growth-inhibitory dose) resulted in significantly increased activity of IRP also in HeLa and THP-1 cells. | Iron | Wnt family member 2 | Homo sapiens |