Title : FK-506 and cyclosporin A potentiate the IgE antibody production by contact sensitization with hapten in mice.

Pub. Date : 1997 Oct

PMID : 9336339






2 Functional Relationships(s)
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1 The expression of interferon-gamma mRNA in reverse transcriptase-polymerase chain reaction in the ear was inhibited by FK-506 and cyclosporin A. Cyclosporine interferon gamma Mus musculus
2 Contrary to the above in vivo findings, the immunosuppressors, FK-506 and cyclosporin A, inhibited the production of interferon-gamma and interleukin-2 by cultured Th1 cells (1E10.H2 cells) and of interleukin-4 and -5 by Th2 cells (D10.G4.1 cells) in vitro. Cyclosporine interferon gamma Mus musculus