Title : Phosphatidylinositol 3-kinase is required for the formation of constitutive transport vesicles from the TGN.

Pub. Date : 1997 Oct 20

PMID : 9334339






1 Functional Relationships(s)
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1 These findings indicate that phosphatidylinositol-3-phosphate (PI[3]P) is required for the formation of TGN-derived exocytic transport vesicles, and that the p62(cplx)-associated PI3-kinase and an activated GTPase are the essential molecules that drive production of this PI(3)P. 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) nucleoporin 62 Homo sapiens