Title : In vivo efficacies of 5'-methylthioadenosine analogs as trypanocides.

Pub. Date : 1997 Oct

PMID : 9333033






1 Functional Relationships(s)
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1 5"-Deoxy-5"-(methylthio)adenosine (MTA), a key by-product of polyamine biosynthesis, is cleaved by MTA phosphorylase and is salvaged as adenine and, through conversion of the ribose moiety, methionine. Polyamines methylthioadenosine phosphorylase Mus musculus