Title : Trimethyltin syndrome as a hippocampal degeneration model: temporal changes and neurochemical features of seizure susceptibility and learning impairment.

Pub. Date : 1997 Dec

PMID : 9330376






2 Functional Relationships(s)
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Protein Name
Organism
1 (1) Morphologically, trimethyltin produced a progressive loss of hippocampal CA3 and CA4 pyramidal cells, starting from four days after peroral treatment with trimethyltin hydroxide (9 mg/kg), as described previously. trimethyltin carbonic anhydrase 3 Rattus norvegicus
2 (4) Neurochemically, trimethyltin treatment caused changes of neurochemical markers, which were manifested by the elevation of neuropeptide Y content in the entorhinal cortex, and of choline acetyltransferase in the hippocampal CA3 subfield. trimethyltin carbonic anhydrase 3 Rattus norvegicus