Title : Cytochrome P450 mediated bioactivation of methyleugenol to 1'-hydroxymethyleugenol in Fischer 344 rat and human liver microsomes.

Pub. Date : 1997 Sep

PMID : 9328175






1 Functional Relationships(s)
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1 Studies undertaken at low substrate concentration (20 microM) with microsomes from livers of rats treated with the enzyme inducers phenobarbital, dexamethasone, isosafrole and isoniazid indicated that a number of cytochrome P450 isozymes can catalyze the high affinity component. Isoniazid cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus