Title : Progesterone inhibits 20alpha-hydroxysteroid dehydrogenase expression in the rat corpus luteum through the glucocorticoid receptor.

Pub. Date : 1997 Oct

PMID : 9322971






3 Functional Relationships(s)
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1 Progesterone inhibits 20alpha-hydroxysteroid dehydrogenase expression in the rat corpus luteum through the glucocorticoid receptor. Progesterone nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus
2 In summary, this report provides the first evidence that despite the absence of the PR in the rat corpus luteum, progesterone can act through the GR to down-regulate the expression of 20alpha-HSD, an enzyme that catabolizes progesterone and reduces progesterone secretion by the corpus luteum. Progesterone nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus
3 In summary, this report provides the first evidence that despite the absence of the PR in the rat corpus luteum, progesterone can act through the GR to down-regulate the expression of 20alpha-HSD, an enzyme that catabolizes progesterone and reduces progesterone secretion by the corpus luteum. Progesterone nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus