Title : cAMP mediates homologous downregulation of PAF receptor mRNA expression in mesangial cells.

Pub. Date : 1997 Sep

PMID : 9321918






1 Functional Relationships(s)
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1 Treatment of the cells with PAF (10(-7)-10(-8) M) reduced the expression of PAF receptor mRNA in 1 h, and this reduction was recovered by pretreatment of mesangial cells with a specific PAF receptor antagonist, WEB-2086 (10(-6) M), or a cyclooxygenase inhibitor, indomethacin (10(-6) M), for 10 min. Indomethacin PCNA clamp associated factor Rattus norvegicus