Title : Biological evaluation of two anomeric glucose analogues iodinated in position 6.

Pub. Date : 1997 Aug

PMID : 9316079






4 Functional Relationships(s)
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1 Two anomeric analogues of glucose labelled with 123 iodine in position 6, proposed as tracers of glucose transport in vivo, have been synthesized: alpha- and beta-methyl-6-deoxy-6-iodo-D-glucopyranoside (alpha MDIG and beta MDIG). Glucose ribosomal oxygenase 2 Homo sapiens
2 Two anomeric analogues of glucose labelled with 123 iodine in position 6, proposed as tracers of glucose transport in vivo, have been synthesized: alpha- and beta-methyl-6-deoxy-6-iodo-D-glucopyranoside (alpha MDIG and beta MDIG). Glucose ribosomal oxygenase 2 Homo sapiens
3 alpha MDIG uptake was lowered in the presence of glucose transport inhibitors in each experimental model. Glucose ribosomal oxygenase 2 Homo sapiens
4 Only alpha MDIG interacts with the glucose transporter, and thus could be used to estimate glucose transport in vivo. Glucose ribosomal oxygenase 2 Homo sapiens