Title : Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters.

Pub. Date : 1997 Sep

PMID : 9315102






2 Functional Relationships(s)
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Protein Name
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1 This induction was dependent upon the expression of c-Fos since AP-1 transcriptional activity was not increased in TPA-treated keratinocytes derived from c-fos null mice. Tetradecanoylphorbol Acetate FBJ osteosarcoma oncogene Mus musculus
2 c-Fos was expressed only in TPA treated keratinocytes, Fra-2 was expressed only in calcium-treated cells, and Fra-1 was expressed in both. Tetradecanoylphorbol Acetate FBJ osteosarcoma oncogene Mus musculus