Title : Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor.

Pub. Date : 1997 Sep

PMID : 9313925






1 Functional Relationships(s)
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1 In this study we have compared the abilities of the enantiomers of the structural isomers of the phenolamines, octopamine and synephrine, and the catecholamines, noradrenaline and adrenaline, to couple selectively a human cloned alpha 2A-adrenoceptor, stably expressed in a Chinese hamster ovary (CHO) cell line, to G-protein linked second messenger pathways mediating an increase and a decrease in cyclic AMP production. Epinephrine adrenoceptor alpha 2A Homo sapiens