Title : A new function of p120-GTPase-activating protein. Prevention of the guanine nucleotide exchange factor-stimulated nucleotide exchange on the active form of Ha-ras p21.

Pub. Date : 1997 Oct 3

PMID : 9312123






2 Functional Relationships(s)
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1 As a consequence of this inhibition, presence of p120-GAP enhanced the regeneration of Ha-Ras.GTPgammaS by GEF at a GDP:GTPgammaS ratio mimicking the in vivo GDP:GTP ratio. Guanosine Diphosphate RAS p21 protein activator 1 Homo sapiens
2 This constrain is likely involved in the regulation of the physiological GDP/GTP cycle of Ras and in the action of p120-GAP as downstream effector of Ras. Guanosine Diphosphate RAS p21 protein activator 1 Homo sapiens