Title : Neural modulation of the antisecretory effect of peptide YY in the rat jejunum.

Pub. Date : 1997 Aug 20

PMID : 9311665






3 Functional Relationships(s)
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1 The aim of the present study was to investigate the mechanisms of the peptide YY effect on vasoactive intestinal peptide (VIP)-stimulated jejunal net water flux in the rat. Water vasoactive intestinal peptide Rattus norvegicus
2 A small peptide YY dose (10 pmol/kg) inhibited significantly (P < 0.005) the jejunal net water flux produced by 30 microg/kg per h of VIP. Water vasoactive intestinal peptide Rattus norvegicus
3 These results suggest that peptide YY inhibits VIP-stimulated jejunal net water flux in vivo through a neural mechanism implicating the participation of nicotinic synapses, alpha2-adrenoceptors and sigma receptors. Water vasoactive intestinal peptide Rattus norvegicus