Title : Hypoxia stimulates proximal tubular cell matrix production via a TGF-beta1-independent mechanism.

Pub. Date : 1997 Sep

PMID : 9291182






1 Functional Relationships(s)
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1 In human PTE, hypoxia (1% O2, 24 hr) increased total collagen production (15%), decreased MMP-2 activity (55% +/- 13%; control = 100%) and increased tissue inhibitor of metalloproteinase-1 (TIMP-1) protein. Oxygen matrix metallopeptidase 2 Homo sapiens